- The role of PP2A in brain microvascular permeabiy
G. Casey, J. P. Spiers. Pharmacology and Therapeutics, Trinity College Dublin, Dublin, Ireland
- The role of rage in the pathogenesis of inflammatory pain in an acute model of inflammation
A. Aibinu1, S. Dolan2. 1GLASGOW CALEDONIAN UNIVERSITY, GLASGOW, United Kingdom, 2SCHOOL OF HEALTH AND LIFE SCIENCES, GLASGOW CALEDONIAN UNIVERSITY, GLASGOW, United Kingdom
- The selectivity of clinically used α-adrenoceptor antagonists, antidepressants and antipsychotics for the human α1A, α1B and α1D-adrenoceptors.
J. G. Baker1, R. G. Proudman1, A. S. Pupo2. 1Cell Signalling, School of Life Sciences, University of Nottingham, Nottingham, United Kingdom, 2Department of Pharmacology, Instituto de Biociencias, Botucatu, SP, Brazil
- The use of complementary biophysical approaches to assess fragment binding to the epigenetic target bromodomain containing protein 3 (BRD3)
J. Lane1, J. Morgan1, A. Scott1, D. Allcock2, C. Sleigh3, S. Pollack1, H. Williams4, D. Ogg5, T. Howard5, J. Brown3, K. Chohan3, S. Paoletta3, M. Abbott5, S. Onions3. 1Bioscience, Sygnature Discovery, Nottingham, United Kingdom, 2Covance Laboratories Ltd., Harrogate, United Kingdom, 3Sygnature Discovery, Nottingham, United Kingdom, 4Centre for Biomolecular Sciences, University of Nottingham, Nottingham, United Kingdom, 5Peak Proteins, Alderley Edge, United Kingdom
- The use of dynamic mass redistribution (dmr) in the european lead factory (elf): a case study
G. L. Baillie, O. L. Watt, S. McElroy. University of Dundee, Newhouse, United Kingdom
- The use of NanoBRET to determine the cooperative effects of allosteric modulators on the binding of a1 adenosine receptor agonists
S. L. Cooper1,2, M. Soave1,2, S. J. Hill1,2, J. Woolard1,2. 1Division of Physiology, Pharmacology and Neuroscience, School of Life Sciences, University of Nottingham, Nottingham, United Kingdom, 2Centre of Membrane Proteins and Receptors, University of Nottingham, Nottingham, United Kingdom
- The utility of CRISPR/Cas technology to uncover the signalling of orphan GPCRs
J. Iyinikkel, J. Hislop, D. Thompson, F. Murray. Metabolic and Cardiovascular Health, University of Aberdeen, Aberdeen, United Kingdom
- The utility of SMALPs for investigating the structure/function of bovine rhodopsin
D. Poyner1, R. T. Logan2, M. Wheatley2, P. J. Reeves3. 1Life and Health Sciences, Aston University, Birmingham, United Kingdom, 2Biosciences, University of Birmingham, Birmingham, United Kingdom, 3School of Biological Sciences, University of Essex, Colchester, United Kingdom
- To compare clinical efficacy of formoterol and fluticasone versus salmeterol and fluticasone in patients of bronchial asthma
A. Rattu1, A. Goel2. 1Pharmacology, Government medical college , amritsar, Amritsar, India, 2Pharmacology, Government medical college , Amritsar, Amritsar, India
- Translational pharmacokinetic-pharmacodynamic analysis of sedative effects in rats and humans using published data
K. Tse1, P. Nordell2, M. Rolf2, W. S. Redfern1. 1Drug Safety and Metabolism, AstraZeneca, Cambridge, United Kingdom, 2Drug Safety and Metabolism, AstraZeneca, M”lndal, Sweden