- Association of Thiopurine S-methyltransferase (TPMT) and cathechol O- methyl-transferase (COMT) variants with cisplatin induced ototoxicity in a UK cohort of paediatric cancer patients
S Thiesen, B Pizer, P Yin, JE Zhang, P Brock, G Makin, S Bailey, S Picton, DA Walker, AL Jorgensen, M Pirmohamed, DB Hawcutt
- Characterization of the specificity and functionality of drug-responsive T-cells isolated piperacillin hypersensitive patients with cystic fibrosis
Z Al-Attar, L Falkner, J Farrell, R Jenkins, X Meng, P Whitaker, D Peckham, K Park, D Naisbitt
- Co-Inhibitory Regulation of Drug-Specific T-Cell Responses
A Gibson, M Ogese, L Faulkner, BK Park, DJ Naisbitt
- Defining The Signals Between Hepatocytes And Immune Cells In Idiosyncratic Drug-induced Liver Injury (DILI)
MO Ogese, L Faulkner, BK Park, C Betts, DJ Naisbitt
- Development of a high-throughput screening assay to discover protein-protein interaction disruptor compounds as a novel anti-fibrosis treatment.
D Tsallos, J Findlay, G Baillie
- Evaluation of an Improved Throughput in-vitro Bone Marrow Toxicity Assay and its Application in Enabling Early Stage Discovery Safety.
A Mead, S Sweeney, J Kelsall, C Walker, M Wagoner, C Sadler
- Investigating the use of Xenopus embryos as a non-mammalian pre-clinical screening tool for the prediction of drug-induced toxicity
K Saide, GN Wheeler, DJ Antoine, V Sherwood
- Mast cell proteases as novel markers for the diagnosis of drug-induced allergic reactions and for predicting susceptibility to severe reactions
RS Abadalkareem, TA Brwon, HS Whitworth, LC Lau, X Zhou, E Eren, AF Walls
- The Role of HMGB1 in Drug-Induced Stevens Johnson Syndrome/ Toxic Epidermal Necrolysis
DF Carr, G Nwikue, DJ Antoine, M Pirmohamed
- The UK Pharmacogenetics and Stratified Medicine Network
CJ McNamee