- Role of arrestins in CXCL12 induced migration in different cancer cell lines
P. Goh, A. Mueller. School of Pharmacy, University of East Anglia, Norwich, United Kingdom,
- Role of Gà C-terminal helix for binding affinity to muscarinic receptors
V. Jelinek, M. Bnemann. Institute of Pharmacology and Clinical Pharmacy, Philipps-Universit„t Marburg, Marburg, Germany,
- Screening of orthosteric antagonists for the pro-inflammatory GPR84 receptor
S. J. Mancini1, J. Mobarec2, R. Newman2, N. Swain2, M. Barnes2, A. Tobin1, G. Milligan1. 1Institute of Molecular, Cell and Systems Biology, University of Glasgow, Glasgow, United Kingdom, 2Heptares Therapeutics, Welwyn Garden City, United Kingdom,
- Systematic mutation reveals different phospho-interaction patterns of beta-arrestin-1 to GPR35 and GPR120
L. Lin, A. Tobin, G. Milligan. Institute of Molecular, Cell and Systems Biology, Glasgow, United Kingdom,
- The affinity and selectivity of orexin A, orexin B and orexin antagonists for the human orexin 1 and orexin 2 receptors.
R. G. Proudman, J. G. Baker. Cell Signalling, University of Nottingham, Nottingham, United Kingdom,
- The human alpha2A-adrenoceptor signals via Gi and Gs proteins.
J. Akinaga1, R. G. Proudman1, J. G. Baker2. 1Cell Signalling, University of Nottingham, Nottingham, United Kingdom, 2University of Nottingham, Nottingham, United Kingdom,
- The impact of linker region between receptor and fluorescent protein on arrestin recruitment assays.
S. Al-Sabah1, M. Bnemann2, C. Krasel2. 1Pharmacology & Toxicology, Kuwait University, Kuwait, Kuwait, 2Institut fr Pharmakologie und Klinische Pharmazie, Philipps-Universit„t Marburg, Marburg, Germany,
- The use of fluorescence correlation spectroscopy to investigate binding site stoichiometry for monomeric and dimeric fluorescent ligands at the neuropeptide Y Y1 receptor
R. R. Richardson1, M. Groenen1, M. Liu2, S. Mountford2, S. Briddon1, P. Thompson2, N. Holliday1. 1SoLS; ICS, University of Nottingham, Nottingham, United Kingdom, 2medicinal chemistry, Monash University, Melbourne, Australia,
- Triazoloquinazolines: dual-target, a2ar - pde 10a, anti-proliferative compounds
I. J. Winfield1,2, D. Safitri1, L. Kalash2, S. Carvalho1, A. Bender2, G. Ladds1. 1Department of Pharmacology, University of Cambridge, Cambridge, United Kingdom, 2Department of Chemistry, University of Cambridge, Cambridge, United Kingdom,
- Unraveling the complex G protein interaction signatures of Free Fatty Acid Receptors using BRET ER/K biosensors
B. Hudson1, A. Butcher2, A. McKenzie1, T. Ulven3, G. Milligan1. 1University of Glasgow, Glasgow, United Kingdom, 2MRC Toxicology Unit, Leicester, United Kingdom, 3Univeristy of Southern Denmark, Odense, Denmark,